Spontaneous Pneumothorax Pathophysiology. Primary spontaneous pneumothorax definition — a primary spontaneous pneumothorax (psp) is traditionally defined as a pneumothorax which presents without. Appropriate treatment of pneumothorax is dictated by the clinical assessment of symptoms, size, and etiology.

The main principle of the pathophysiology of spontaneous pneumothorax revolves around gas leaking into the pleural space. A pneumothorax occurs when air leaks into the space between your lung and chest wall.